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pentobarbital will lower the extent or outcome of zolpidem by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Not known.Check Intently (one)pentobarbital will lessen the level or influence of fentanyl intranasal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of